Biology › Gene regulation, genomics and biotechnology

Gene regulation, genomics and biotechnology

Unit B17 · 6 lessons.

Notes

Illustrated notes for each topic in this unit, with worked examples and a checklist of objectives.

• Control of gene expression
  Transcription factors and how they change the rate of transcription of a specific gene, the lac operon as the prokaryotic worked example, oestrogen…
• Mutation, gene expression and cancer
  Types of gene mutation and their consequences at protein level, why many substitutions are silent, the difference between a mutation in a gene and…
• Recombinant DNA technology
  Obtaining a gene by reverse transcriptase from mRNA, by restriction endonucleases and by the gene machine; sticky ends and DNA ligase; plasmid…
• Genome analysis, genetic screening and gene therapy
  DNA sequencing and what a genome project produces; DNA probes and microarrays; genetic screening and the role of genetic counselling; DNA profiling…
• Industrial biotechnology and fermentation
  Why industry uses microorganisms rather than plants or animals, mycoprotein and single-cell protein as food with the arguments on both sides; the…
• Pharming, recombinant medicines and synthetic biology
  Factor VIII and adenosine deaminase as recombinant medicines and why cell culture replaced blood products, pharming through a mammary-specific…