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OCR A-level Biology A questions by topic
Our topic questions for OCR A-level Biology A (H420), sorted under the sections of OCR’s Biology A specification in the order it prints them. Every question is original, with a point-by-point mark scheme, and every set has a printable PDF.
Other specifications: AQA A-level Biology · Cambridge A-level Biology · Edexcel A-level Biology A · Edexcel A-level Biology B · every topic, by unit
Module 1: Development of practical skills in biology
1.1 Practical skills assessed in a written examination50 questions3 topics
- Variables and controls: what an experiment can show20 questions · 64 marks · 1.1 · PDF, 61 KB
- Handling data: units, scales, rates and uncertainty15 questions · 49 marks · 1.1 · PDF, 75 KB
- Averages, spread and the null hypothesis15 questions · 50 marks · 1.1 · PDF, 54 KB
1.2 Practical skills assessed in the practical endorsementno questions yet
We have no topic questions for this section yet.
Module 2: Foundations in biology
2.1.1 Cell structure74 questions4 topics
- Eukaryotic cell structure and organelles20 questions · 61 marks · 2.1.1 · PDF, 55 KB
- Microscopy, magnification and resolution15 questions · 48 marks · 2.1.1 · PDF, 49 KB
- Prokaryotic cells and viruses21 questions · 64 marks · 2.1.1 · PDF, 80 KB
- Cell specialisation and biological organisation18 questions · 58 marks · 2.1.1 · PDF, 56 KB
2.1.2 Biological molecules117 questions7 topics
- Water and inorganic ions15 questions · 46 marks · 2.1.2 · PDF, 51 KB
- Carbohydrate structure and function22 questions · 73 marks · 2.1.2 · PDF, 80 KB
- Lipids: triglycerides, phospholipids and ester bonds15 questions · 44 marks · 2.1.2 · PDF, 53 KB
- Protein structure and function15 questions · 49 marks · 2.1.2 · PDF, 54 KB
- Membrane structure and the fluid mosaic model15 questions · 48 marks · 2.1.2 · PDF, 51 KB
- Diet, energy and how to read a health claim20 questions · 73 marks · 2.1.2 · PDF, 82 KB
- Cholesterol, atheroma and what a risk factor means15 questions · 59 marks · 2.1.2 · PDF, 75 KB
2.1.3 Nucleotides and nucleic acids75 questions5 topics
- DNA and RNA structure15 questions · 48 marks · 2.1.3 · PDF, 72 KB
- DNA replication15 questions · 48 marks · 2.1.3 · PDF, 75 KB
- The genetic code and transcription15 questions · 49 marks · 2.1.3 · PDF, 54 KB
- Translation and protein synthesis15 questions · 51 marks · 2.1.3 · PDF, 76 KB
- Glycolysis, ATP and the link reaction15 questions · 47 marks · 2.1.3 · PDF, 55 KB
2.1.4 Enzymes78 questions5 topics
- Enzyme action and specificity15 questions · 48 marks · 2.1.4 · PDF, 74 KB
- Factors affecting enzyme rate: temperature, pH and concentration18 questions · 60 marks · 2.1.4 · PDF, 57 KB
- Enzyme inhibition and metabolic control15 questions · 49 marks · 2.1.4 · PDF, 74 KB
- Cofactors, coenzymes and where enzymes work15 questions · 45 marks · 2.1.4 · PDF, 73 KB
- Digestion and absorption in the human gut15 questions · 53 marks · 2.1.4 · PDF, 52 KB
2.1.5 Biological membranes60 questions4 topics
- Membrane structure and the fluid mosaic model15 questions · 48 marks · 2.1.5 · PDF, 51 KB
- Diffusion and osmosis15 questions · 51 marks · 2.1.5 · PDF, 55 KB
- Active transport, co-transport and bulk transport15 questions · 48 marks · 2.1.5 · PDF, 77 KB
- Digestion and absorption in the human gut15 questions · 53 marks · 2.1.5 · PDF, 52 KB
2.1.6 Cell division, cell diversity and cellular organisation106 questions6 topics
- The cell cycle and mitosis17 questions · 57 marks · 2.1.6 · PDF, 55 KB
- Meiosis and the sources of genetic variation18 questions · 59 marks · 2.1.6 · PDF, 58 KB
- Cell specialisation and biological organisation18 questions · 58 marks · 2.1.6 · PDF, 56 KB
- Stem cells and cell potency15 questions · 51 marks · 2.1.6 · PDF, 53 KB
- Xylem and the transpiration stream23 questions · 73 marks · 2.1.6 · PDF, 84 KB
- Transpiration and stomatal control15 questions · 50 marks · 2.1.6 · PDF, 72 KB
Module 3: Exchange and transport
3.1.1 Exchange surfaces59 questions3 topics
- Surface area to volume ratio: why size limits diffusion15 questions · 48 marks · 3.1.1 · PDF, 76 KB
- Gas exchange in mammals: lungs and ventilation26 questions · 96 marks · 3.1.1 · PDF, 86 KB
- Gas exchange in insects, fish and plants18 questions · 56 marks · 3.1.1 · PDF, 58 KB
3.1.2 Transport in animals45 questions3 topics
- The heart and cardiac cycle15 questions · 50 marks · 3.1.2 · PDF, 71 KB
- Blood vessels, tissue fluid and lymph15 questions · 51 marks · 3.1.2 · PDF, 74 KB
- Haemoglobin and oxygen dissociation curves15 questions · 51 marks · 3.1.2 · PDF, 51 KB
3.1.3 Transport in plants86 questions5 topics
- Xylem and the transpiration stream23 questions · 73 marks · 3.1.3 · PDF, 84 KB
- Transpiration and stomatal control15 questions · 50 marks · 3.1.3 · PDF, 72 KB
- Phloem translocation and the mass-flow hypothesis15 questions · 48 marks · 3.1.3 · PDF, 75 KB
- Plan diagrams and tissue sections15 questions · 47 marks · 3.1.3 · PDF, 53 KB
- Gas exchange in insects, fish and plants18 questions · 56 marks · 3.1.3 · PDF, 58 KB
Module 4: Biodiversity, evolution and disease
4.1.1 Communicable diseases, disease prevention and the immune system200 questions11 topics
- Pathogens and non-specific defences21 questions · 71 marks · 4.1.1 · PDF, 59 KB
- The specific immune response17 questions · 61 marks · 4.1.1 · PDF, 53 KB
- Antibodies, vaccination and the four kinds of immunity19 questions · 67 marks · 4.1.1 · PDF, 79 KB
- Evidence for evolution, resistance and genetic drift25 questions · 85 marks · 4.1.1 · PDF, 68 KB
- Enzyme inhibition and metabolic control15 questions · 49 marks · 4.1.1 · PDF, 74 KB
- Infectious disease: transmission and control19 questions · 68 marks · 4.1.1 · PDF, 59 KB
- Plant disease and plant defences15 questions · 49 marks · 4.1.1 · PDF, 53 KB
- Plan diagrams and tissue sections15 questions · 47 marks · 4.1.1 · PDF, 53 KB
- Conservation in situ and ex situ15 questions · 55 marks · 4.1.1 · PDF, 54 KB
- Industrial biotechnology and fermentation24 questions · 84 marks · 4.1.1 · PDF, 88 KB
- Genome analysis, genetic screening and gene therapy15 questions · 53 marks · 4.1.1 · PDF, 53 KB
4.2.1 Biodiversity56 questions3 topics
- Measuring biodiversity15 questions · 52 marks · 4.2.1 · PDF, 72 KB
- Conservation in situ and ex situ15 questions · 55 marks · 4.2.1 · PDF, 54 KB
- The carbon cycle and climate change26 questions · 90 marks · 4.2.1 · PDF, 66 KB
4.2.2 Classification and evolution102 questions6 topics
- Classification, phylogeny and molecular evidence15 questions · 50 marks · 4.2.2 · PDF, 53 KB
- Natural selection: variation, selection and allele frequency15 questions · 49 marks · 4.2.2 · PDF, 56 KB
- Evidence for evolution, resistance and genetic drift25 questions · 85 marks · 4.2.2 · PDF, 68 KB
- Averages, spread and the null hypothesis15 questions · 50 marks · 4.2.2 · PDF, 54 KB
- Continuous and discontinuous variation16 questions · 52 marks · 4.2.2 · PDF, 54 KB
- The five kingdoms, species concepts and viruses16 questions · 57 marks · 4.2.2 · PDF, 54 KB
Module 5: Communication, homeostasis and energy (A-level only)
5.1.1 Communication and homeostasis70 questions4 topics
- Hormonal communication and negative feedback15 questions · 48 marks · 5.1.1 · PDF, 54 KB
- Receptors: transduction and the reflex arc21 questions · 76 marks · 5.1.1 · PDF, 64 KB
- The synapse: transmission, and why it runs one way19 questions · 65 marks · 5.1.1 · PDF, 58 KB
- Thermoregulation in endotherms and ectotherms15 questions · 50 marks · 5.1.1 · PDF, 54 KB
5.1.2 Excretion as an example of homeostatic control64 questions4 topics
- Osmoregulation and kidney function15 questions · 54 marks · 5.1.2 · PDF, 74 KB
- Regulation of blood glucose and diabetes mellitus15 questions · 57 marks · 5.1.2 · PDF, 74 KB
- Antibodies, vaccination and the four kinds of immunity19 questions · 67 marks · 5.1.2 · PDF, 79 KB
- The liver: detoxification, deamination and the making of urea15 questions · 52 marks · 5.1.2 · PDF, 56 KB
5.1.3 Neuronal communication75 questions4 topics
- Receptors: transduction and the reflex arc21 questions · 76 marks · 5.1.3 · PDF, 64 KB
- The action potential and its propagation16 questions · 56 marks · 5.1.3 · PDF, 74 KB
- The synapse: transmission, and why it runs one way19 questions · 65 marks · 5.1.3 · PDF, 58 KB
- Organisation of the nervous system19 questions · 64 marks · 5.1.3 · PDF, 57 KB
5.1.4 Hormonal communication67 questions4 topics
- Hormonal communication and negative feedback15 questions · 48 marks · 5.1.4 · PDF, 54 KB
- Regulation of blood glucose and diabetes mellitus15 questions · 57 marks · 5.1.4 · PDF, 74 KB
- Recombinant DNA technology22 questions · 80 marks · 5.1.4 · PDF, 63 KB
- Stem cells and cell potency15 questions · 51 marks · 5.1.4 · PDF, 53 KB
5.1.5 Plant and animal responses142 questions8 topics
- Plant responses: tropisms, auxins and the classic experiments23 questions · 77 marks · 5.1.5 · PDF, 65 KB
- Receptors: transduction and the reflex arc21 questions · 76 marks · 5.1.5 · PDF, 64 KB
- The synapse: transmission, and why it runs one way19 questions · 65 marks · 5.1.5 · PDF, 58 KB
- Muscles and movement: the sliding-filament model15 questions · 53 marks · 5.1.5 · PDF, 53 KB
- The heart and cardiac cycle15 questions · 50 marks · 5.1.5 · PDF, 71 KB
- Hormonal communication and negative feedback15 questions · 48 marks · 5.1.5 · PDF, 54 KB
- Organisation of the nervous system19 questions · 64 marks · 5.1.5 · PDF, 57 KB
- Plant disease and plant defences15 questions · 49 marks · 5.1.5 · PDF, 53 KB
5.2.1 Photosynthesis69 questions3 topics
- Chloroplast structure and the light-dependent reactions18 questions · 60 marks · 5.2.1 · PDF, 58 KB
- The Calvin cycle26 questions · 96 marks · 5.2.1 · PDF, 62 KB
- Limiting factors and primary productivity25 questions · 96 marks · 5.2.1 · PDF, 87 KB
5.2.2 Respiration48 questions3 topics
- Glycolysis, ATP and the link reaction15 questions · 47 marks · 5.2.2 · PDF, 55 KB
- The Krebs cycle and oxidative phosphorylation15 questions · 54 marks · 5.2.2 · PDF, 56 KB
- Anaerobic respiration and the respiratory quotient18 questions · 63 marks · 5.2.2 · PDF, 55 KB
Module 6: Genetics, evolution and ecosystems (A-level only)
6.1.1 Cellular control98 questions6 topics
- Control of gene expression15 questions · 53 marks · 6.1.1 · PDF, 52 KB
- Mutation, gene expression and cancer21 questions · 75 marks · 6.1.1 · PDF, 82 KB
- The cell cycle and mitosis17 questions · 57 marks · 6.1.1 · PDF, 55 KB
- Hormonal communication and negative feedback15 questions · 48 marks · 6.1.1 · PDF, 54 KB
- Homeobox genes, Hox genes and apoptosis15 questions · 45 marks · 6.1.1 · PDF, 53 KB
- The genetic code and transcription15 questions · 49 marks · 6.1.1 · PDF, 54 KB
6.1.2 Patterns of inheritance139 questions8 topics
- Meiosis and the sources of genetic variation18 questions · 59 marks · 6.1.2 · PDF, 58 KB
- Monohybrid inheritance and genetic diagrams21 questions · 74 marks · 6.1.2 · PDF, 55 KB
- Dihybrid inheritance, linkage, epistasis and the chi-squared test15 questions · 49 marks · 6.1.2 · PDF, 77 KB
- Population genetics and Hardy-Weinberg equilibrium15 questions · 50 marks · 6.1.2 · PDF, 56 KB
- Natural selection: variation, selection and allele frequency15 questions · 49 marks · 6.1.2 · PDF, 56 KB
- Evidence for evolution, resistance and genetic drift25 questions · 85 marks · 6.1.2 · PDF, 68 KB
- Speciation and reproductive isolation15 questions · 53 marks · 6.1.2 · PDF, 80 KB
- Artificial selection and selective breeding15 questions · 53 marks · 6.1.2 · PDF, 56 KB
6.1.3 Manipulating genomes54 questions3 topics
- Genome analysis, genetic screening and gene therapy15 questions · 53 marks · 6.1.3 · PDF, 53 KB
- Recombinant DNA technology22 questions · 80 marks · 6.1.3 · PDF, 63 KB
- Pharming, recombinant medicines and synthetic biology17 questions · 57 marks · 6.1.3 · PDF, 56 KB
6.2.1 Cloning and biotechnology84 questions5 topics
- Enzyme inhibition and metabolic control15 questions · 49 marks · 6.2.1 · PDF, 74 KB
- Populations and their limits15 questions · 54 marks · 6.2.1 · PDF, 54 KB
- Stem cells and cell potency15 questions · 51 marks · 6.2.1 · PDF, 53 KB
- Cloning in plants and animals15 questions · 51 marks · 6.2.1 · PDF, 54 KB
- Industrial biotechnology and fermentation24 questions · 84 marks · 6.2.1 · PDF, 88 KB
6.3.1 Ecosystems124 questions6 topics
- Populations and their limits15 questions · 54 marks · 6.3.1 · PDF, 54 KB
- Limiting factors and primary productivity25 questions · 96 marks · 6.3.1 · PDF, 87 KB
- Nutrient cycles: nitrogen, phosphorus and eutrophication15 questions · 53 marks · 6.3.1 · PDF, 54 KB
- Succession and environmental change28 questions · 99 marks · 6.3.1 · PDF, 93 KB
- Measuring biodiversity15 questions · 52 marks · 6.3.1 · PDF, 72 KB
- The carbon cycle and climate change26 questions · 90 marks · 6.3.1 · PDF, 66 KB
6.3.2 Populations and sustainability93 questions5 topics
- Populations and their limits15 questions · 54 marks · 6.3.2 · PDF, 54 KB
- Conservation in situ and ex situ15 questions · 55 marks · 6.3.2 · PDF, 54 KB
- Succession and environmental change28 questions · 99 marks · 6.3.2 · PDF, 93 KB
- Measuring biodiversity15 questions · 52 marks · 6.3.2 · PDF, 72 KB
- Managing ecosystems sustainably20 questions · 73 marks · 6.3.2 · PDF, 58 KB
A topic is listed under every section its lesson teaches, so some appear more than once. The codes beside each one are the specification headings it covers in that section.
The sections and codes are OCR’s, so check the current specification when a mark depends on one. The H020/H420 route map lists every heading, with the lessons that teach it.